Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters

This study aimed to determine endocrine disruptors in urbanized rivers Maracanã and Mangue Channel Rio de Janeiro the second most populated city Brazil. Bisphenol A, 17β-estradiol, estriol, 17α-ethinylestradiol were determined by high-performance liquid chromatography with a diode array detector fluorescence In addition, evaluation of estrogenic activity was performed YES bioassay (Yeast estrogen screen) Saccharomyces cerevisiae yeast, acute toxicity assays using Daphnia similis Vibrio fischeri. Estrogenic water samples ranged from below limit detection (<LD) 1.6 ng L-1, while bisphenol A 22.3 1325.2 L-1 estrogens 17β-estradiol <LD 55.2 estriol 313.7 17α-ethinylestradiol, 409.4 L-1. The not detected both analyzed organisms. present indicates serious level pollution compounds evaluated significant risks aquatic ecosystem, mainly for Guanabara Bay which receives river discharge. Therefore, recommending need systematic monitoring mitigating actions these bodies.